October 18-20 | Tucson, AZ

The Research Institution GAP Fund and Accelerator Program Summit

NSF awards 12 new Regional Innovation Engines to fuel research, jobs and economic growth nationwide | NSF – U.S. National Science Foundation

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October 16-17, 2025 / Seattle, WA

The annual summit for research institution gap fund and accelerator programs, including proof of concept programs, startup accelerators, and university venture funds

The Story

The newest NSF Engines awards span critical technologies and applications ranging from enhancing energy grid security to maximizing the yield of critical mineral mining extraction to advancing quantum computing. Each team, led by a coalition of regional organizations, including universities, nonprofits and private industry, will initially receive an award of $15 million over two years. Teams that demonstrate progress on well-defined milestones will have the potential to eventually receive up to $160 million each from NSF over the next decade as they seek to build an internationally competitive technology and innovation cluster in their region.

No single region can solve America’s technology challenges alone. NSF Engines are designed as a connected national network, linking complementary regional strengths. Together, they build domestic supply chains, fill capability gaps and accelerate technology advancement across key sectors and regions.

The NSF Engines program is beginning to demonstrate significant returns and impacts as a result of the nation’s investment via the inaugural NSF Engines funded two years ago. To date, an initial investment of $135 million in taxpayers’ dollars across nine inaugural NSF Engines has garnered more than $2 billion in matching commitments from private industry, philanthropy and state and local governments. These investments are also advancing technologies that maintain American competitiveness in critical areas, including advanced chipmaking, next-generation artificial intelligence, agriculture and food production, disaster preparedness and energy storage. This cohort of NSF Engines coincides with another round of funding released this summer for the inaugural NSF Engines that have demonstrated sustained progress over the first two years of performance.

The 12 newest NSF Engines are:

NSF STELLAR Engine in the Rochester/Finger Lakes Region of New York, led by the University of Rochester.

NSF BRIDGES Engine in Alabama and Tennessee, led by the HudsonAlpha Institute for Biotechnology.

NSF Critical Materials Crossroads Engine in the Kansas City Region, led by the University of Missouri-Kansas City.

NSF Critical Mineral Accelerator Engine in Alaska, led by the University of Alaska Fairbanks.

NSF FAST Engine in Oregon, led by Oregon State University.

NSF Grid Modernization Engine in the Carolinas, led by the University of North Carolina at Charlotte.

NSF IMPACT Engine in Indiana, led by Indiana University.

NSF NEO-SMART Engine in Northeast Ohio, led by Case Western Reserve University with more than 70 regional partners.

NSF Quantum Technologies Engine in Connecticut, led by the University of Connecticut.

NSF RETI Engine in West Virginia and western Pennsylvania, led by West Virginia University in collaboration with the University of Pittsburgh, Carnegie Mellon University and the U.S. Research Impact Alliance.

NSF RuralSTAMINA Biomanufacturing Engine in Iowa and Nebraska, led by Iowa State University.

NSF Seafood Engine in New England, led by the Northeastern Regional Association of Coastal Ocean Observing Systems.

Source: NSF awards 12 new Regional Innovation Engines to fuel research, jobs and economic growth nationwide | NSF – U.S. National Science Foundation

Consortium For Gap Fund and Accelerator ProgramS

The Consortium provides a dedicated, institutional coordinating forum for collective insight, program refinement, and structured engagement with aligned commercial, investment, and philanthropic partners.

GAP are an interdependent institutional innovation and capital strategy that includes:

  • Translational research

  • Proof of concept programs

  • Startup accelerators

  • University venture funds

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